Anna Allen (Alpha, DePauw University) was born in Greencastle, Indiana in 1870, where she would live her entire life. Growing up, Anna was childhood friends with fellow Founders Bessie Grooms (Alpha, DePauw University) and Olive Burnett (Alpha, DePauw University). Musically gifted from an early age, Anna enrolled and became the youngest student to do advanced work at DePauw University's School of Music, entering at the age of 15 and graduating in 1889, at 19. In her junior year, she began teaching pianoforte at the School of Music and continued to hold that position until 1896. She was known as "a student of exceptional ability and rare self-possession, as a brilliant performer and an excellent accompanist."
Living in Greencastle, Anna continued to be highly involved in Alpha Chi Omega as an alumna. Her family regularly made their home available for chapter events - the first national convention was even held there in 1891. Because of her close proximity to the University, Anna was the Founder most closely associated with Alpha chapter and she served as a guide and counselor to the chapter members. It is said that she remained close to "every girl that Alpha initiated until her death, and it was rare when she forgot a face or a name."
Sometime after her graduation, although the precise date is unknown, Anna married Harry M. Smith. They did not have any children. Unfortunately, Harry was seriously ill for many years and many of her friends believed the stress of caring for him sapped Anna of her vitality as well. She died suddenly of "a stroke of apoplexy" on May 23, 1932.